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STABILITY Investigators Selected Research

darapladib

12/2021Interleukin 6 and Cardiovascular Outcomes in Patients With Chronic Kidney Disease and Chronic Coronary Syndrome.
1/2020Prediction of Residual Risk by Ceramide-Phospholipid Score in Patients With Stable Coronary Heart Disease on Optimal Medical Therapy.
1/2020In patients with stable coronary heart disease, low-density lipoprotein-cholesterol levels < 70 mg/dL and glycosylated hemoglobin A1c < 7% are associated with lower major cardiovascular events.
1/2019Characterization of cardiovascular clinical events and impact of event adjudication on the treatment effect of darapladib versus placebo in patients with stable coronary heart disease: Insights from the STABILITY trial.
10/2017Inflammatory Biomarkers Interleukin-6 and C-Reactive Protein and Outcomes in Stable Coronary Heart Disease: Experiences From the STABILITY (Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy) Trial.
10/2017Visit-to-visit variability of blood pressure and cardiovascular outcomes in patients with stable coronary heart disease. Insights from the STABILITY trial.
8/2017Self-Reported Health and Outcomes in Patients With Stable Coronary Heart Disease.
1/2017Growth Differentiation Factor 15 Predicts All-Cause Morbidity and Mortality in Stable Coronary Heart Disease.
7/2016Dietary patterns and the risk of major adverse cardiovascular events in a global study of high-risk patients with stable coronary heart disease.
1/2016Lipoprotein-Associated Phospholipase A2 Activity Is a Marker of Risk But Not a Useful Target for Treatment in Patients With Stable Coronary Heart Disease.
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STABILITY Investigators Research Topics

Disease

11Coronary Disease (Coronary Heart Disease)
01/2020 - 05/2014
8Myocardial Infarction
12/2021 - 05/2014
8Atherosclerotic Plaque (Atheroma)
12/2021 - 05/2014
8Stroke (Strokes)
12/2021 - 05/2014
4Heart Failure
01/2020 - 01/2016
3Inflammation (Inflammations)
12/2021 - 10/2017
2Dyslipidemias (Dyslipidemia)
01/2020 - 10/2017
2Neoplasms (Cancer)
10/2017 - 01/2017
1Cardiovascular Diseases (Cardiovascular Disease)
12/2021
1Chronic Renal Insufficiency
12/2021
1Necrosis
01/2020
1Atherosclerosis
10/2017
1Tooth Loss
10/2017
1Sudden Death
01/2017
1Coronary Artery Disease (Coronary Atherosclerosis)
07/2016

Drug/Important Bio-Agent (IBA)

11darapladibIBA
12/2021 - 05/2014
5Biomarkers (Surrogate Marker)IBA
01/2020 - 01/2016
4omega-Chloroacetophenone (Mace)IBA
12/2021 - 07/2016
4Interleukin-6 (Interleukin 6)IBA
12/2021 - 10/2017
4C-Reactive ProteinIBA
01/2020 - 01/2017
41-Alkyl-2-acetylglycerophosphocholine Esterase (PAF Acetylhydrolase)IBA
01/2020 - 05/2014
3Brain Natriuretic Peptide (Natrecor)FDA Link
01/2020 - 01/2017
2LDL CholesterolIBA
01/2020 - 01/2020
2Growth Differentiation Factor 15IBA
10/2017 - 01/2017
1Phospholipids (Phosphatides)FDA LinkGeneric
01/2020
1Glycated Hemoglobin (Glycosylated Hemoglobin)IBA
01/2020
1CeramidesIBA
01/2020
1pro-brain natriuretic peptide (1-76)IBA
10/2017
1Cystatin CIBA
01/2017
1Troponin T (Troponin T1)IBA
01/2017
1EnzymesIBA
05/2014

Therapy/Procedure

7Therapeutics
12/2021 - 07/2016
1Secondary Prevention
07/2016